Parasitic worms are responsible for more than one billion human infections globally and have a devastating impact on livestock and agriculture. WormBase ParaSite facilitates new approaches to the study and control of parasitic worms by integrating, analysing and displaying genomic data for hundreds of species. At also serves as a foundation for comparative genomics, enabling deep explorations of genome evolution across all roundworms and flatworms and, more broadly, across other animal taxa.
You will work on a range of data analysis, data integration and community-engagement activities for WormBase ParaSite, and will also actively participate in the exciting next phase of development for the resource. The main areas of focus will be:
Customisation and deployment of annotation pipelines for parasitic worm genomes
Analysis, curation and integration of large-scale genomics data sets (e.g. studies of gene expression and genomic variation)
Community engagement, including presentations and training workshops at conferences
WormBase ParaSite is a sister project to the well-known WormBase (www.wormbase.org) and Ensembl (www.ensembl.org) projects. As well as working with genome scientists within the Parasite genomics team, you will also collaborate closely with WormBase and Ensembl staff at the neighbouring European Bioinformatics Institute (EMBL-EBI).
Essential Skills
Programming/scripting experience (e.g. Perl, Python)
Experience with relational databases (MySQL or Postgres)
Proficiency in Unix/Linux operating system
Excellent communication skills
Attention to detail
Ideal Skills
Bioinformatics experience at Masters or PhD level
Experience analysing functional genomics experiments (especially RNASeq)
Knowledge of parasitology, preferably helminths
Experience with genome annotation methodologies and pipelines
Experience with the Ensembl genomics infrastructure
Other information
The Wellcome Sanger Institute is a charitably funded research centre and committed to training the next generation of genome scientists. Focused on understanding the role of genetics in health and disease and a world leader in the genomic revolution, our mission is to use genome sequences to advance understanding of human and pathogen biology in order to improve human health. We aim to provide results that can be translated into diagnostics, treatments or therapies that reduce global health burdens. Our science is large-scale and organised into Programmes, led by our Faculty who conceive and deliver our science, and supported by our Scientific Operations teams responsible for all data production pipelines at the Institute.
Our Campus:
Set over 125 acres, the stunning and dynamic Wellcome Genome Campus is the biggest aggregate concentration of people in the world working on the common theme of Genomes and BioData. It brings together a diverse and exceptional scientific community, committed to delivering life-changing science with the reach, scale and imagination to pursue some of humanity’s greatest challenges.
Our Benefits:
Our employees have access to a comprehensive range of benefits and facilities including:
Group Defined Contribution Pension Scheme and Life Assurance
Group Income Protection
Private Health Insurance
25 days annual leave, increasing by one day a year to a maximum of 30
Family friendly environment including options for flexible and part-time working, a childcare voucher scheme, Campus Nursery and Summer holiday club
Two days paid Employee Volunteering Leave a year
Employee Discount Scheme
Campus Gym, tennis courts and sports hall plus a range of dining facilities
Active Campus Sports and Social Club
Free Campus Bus Service
Genome Research Limited hold an Athena SWAN Bronze Award and will consider all individuals without discrimination and are committed to creating an inclusive environment for all employees, where everyone can thrive.
Please include a covering letter and CV with your application. Closing date for applications: 28th June 2019
Click here to Apply Online